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ltaiana
Beiträge: 1 | Zuletzt Online: 29.01.2024
Registriert am:
26.01.2024
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    • ltaiana hat einen neuen Beitrag "Winter 2024" geschrieben. 26.01.2024

      Halin: Morbus Crohn
      - could tell everything I knew about the disease
      - about NOD2 / pattern recognition receptors in general: what do they recognize?
      - what happens if a bacterium reaches the submucosa?
      - why are TH1 / TH17 responses mounted? what cytokines are released? what are the effects?
      - do you know a disease where IL-17 plays a role in the disease pathology?
      - what happens in the presence of non- invasive bacteria?

      Neri: Clearance of therapeutic proteins
      - how are small molecules / big molecules excreted? (small: kidney, big: liver)
      - why do antibodies have a long half-life?
      - explanation of FcRn recycling
      - do you know of any therapeutic proteins that have a short half-life?
      - Abciximab: Fab-fragment hat binds GPIIb/IIIa repector on platelets and inhibits platelet aggregation
      - why does plattelet aggregation returns to normal only after 4-5d? (due to its high affinity)

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